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There is absolutely no reason to use different nozzles, not even if filaments do require different temperatures. The only exception is when printing abrasive filaments (such as glow-in-the-dark and carbon-fiber) in which case you should use an abrasion-resistant, stainless steel nozzle. This nozzle can also be used to to print “regular” filaments but a regular brass nozzle has slightly more favorable properties if you do not require abrasion resistance.

Also, thanks to the larger nozzle diameter there will be more solid material to cool down which may increase warping. This might be an issue for materials prone to warping during print, like ABS or PC Blend.

On the other end of the spectrum, larger nozzles (again, of those commercially available) range up to 1.2mm. These allow for quicker, larger prints, generally speaking.

From the our website, the following interesting image is shown, comparing the wear resistance of the various nozzle materials up to 0.5 mm ( brass, stainless steel and hardened steel by printing respectively 0.3 kg, 1.0 kg and 4 kg of carbon fibre filled filament):

If you want to use a nozzle with a different diameter than the ones we already mentioned, you have to create the profile in PrusaSlicer manually. Starting with your standard 0.4 mm nozzle, you have to change the nozzle diameter in the Printer Settings and Extrusion width (percentage-wise). Keep in mind that the maximal layer height is always around 80% of the nozzle diameter. For more information, please see Creating profiles for different nozzles.

Range of Options Nozzles come in lots of different shapes and sizes, but they all perform the same function. The smallest nozzles (at least that are commercially available) are 0.15mm — good for very intricate prints, though they can be difficult to calibrate and use. On the other end of the spectrum, larger nozzles (again, of those commercially available) range up to 1.2mm. These allow for quicker, larger prints, generally speaking.
compatible with E3D nozzles.

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